Chief Scientific Officer

SystImmune⠀Inc. is a⠀clinical-stage⠀biopharmaceutical⠀company⠀located in⠀Redmond,⠀WA. It⠀specializes⠀in⠀developing⠀innovative⠀cancer⠀treatments⠀using its⠀established⠀drug⠀development⠀platforms,⠀focusing⠀on⠀bi-specific,⠀multi-specific⠀antibodies,⠀and⠀antibody-drug⠀conjugates⠀(ADCs).⠀SystImmune⠀has⠀several⠀assets in⠀various⠀stages of⠀clinical⠀trials for⠀solid⠀tumor and⠀hematologic⠀indications.⠀Alongside⠀ongoing⠀clinical⠀trials,⠀SystImmune⠀has a⠀strong⠀preclinical⠀pipeline⠀of⠀potential⠀cancer⠀therapeutics⠀in the⠀discovery⠀or⠀IND-enabling⠀stages,⠀representing⠀cutting-edge⠀biologics⠀development.

Summary:

SystImmune⠀is⠀currently⠀searching⠀for a⠀Chief⠀Scientific⠀Officer⠀(CSO) with⠀proven⠀leadership⠀experience⠀in drug⠀development⠀and⠀expertise⠀in the⠀fields of⠀immuno-oncology⠀and⠀antibody⠀therapeutics.⠀The ideal⠀candidate⠀should⠀have⠀experience⠀working in⠀both⠀pharmaceutical⠀and⠀biopharmaceutical⠀organizations,⠀as well as⠀significant⠀experience⠀in drug⠀development⠀from⠀discovery⠀through⠀marketing⠀approval.

The⠀CSO will⠀be⠀responsible⠀for⠀developing⠀SystImmune's⠀strategic⠀scientific⠀roadmap,⠀which⠀includes⠀research⠀activities⠀that⠀support⠀the⠀company's⠀portfolio⠀strategy.⠀This⠀individual⠀will⠀engage and⠀develop⠀scientific⠀partnerships⠀with⠀academic⠀and other⠀organizations/institutions⠀to stay at⠀the⠀forefront⠀of⠀scientific⠀discovery.

In⠀addition⠀to this,⠀the CSO⠀will⠀leverage⠀global⠀partners⠀in the⠀Biokin⠀Pharmaceutical⠀Group, and⠀external⠀contract⠀research⠀organizations⠀(CROs),⠀and⠀establish⠀internal⠀drug⠀discovery⠀capabilities⠀to⠀maintain⠀an⠀industry-leading⠀preclinical⠀pipeline.

Essential Duties and Responsibilities:

• Lead and⠀manage⠀SystImmune's⠀R&D⠀preclinical⠀efforts,⠀collaborating⠀closely⠀with each⠀department⠀head to⠀ensure⠀alignment⠀with the⠀company's⠀strategy⠀and⠀timeline.
• Establish⠀program⠀milestones⠀and⠀timelines⠀in⠀collaboration⠀with⠀department⠀heads and⠀drive⠀programs⠀through⠀solid⠀leadership,⠀empowerment,⠀and⠀accountability,⠀ensuring⠀that⠀portfolio⠀goals are⠀met on⠀time and⠀within⠀budget.
• Oversee⠀the R&D⠀team's⠀finalization⠀of⠀nonclinical⠀study⠀reports⠀and⠀contribute⠀to the⠀writing of⠀regulatory⠀documents⠀for⠀clinical⠀studies.
• Contribute⠀to⠀evaluating⠀the⠀intellectual⠀property⠀landscape⠀for all⠀products⠀at an⠀early⠀stage.
• Develop⠀a strategy⠀for⠀building⠀out⠀internal⠀drug⠀discovery⠀capabilities⠀and/or⠀leveraging⠀external⠀contract⠀research⠀organizations⠀(CROs).
• Develop⠀short- and⠀long-term⠀scientific⠀objectives⠀for the⠀organization⠀that cover⠀discovery,⠀development,⠀manufacturing,⠀licensing/approval,⠀and⠀commercialization⠀of⠀products⠀aligned⠀with the⠀company's⠀portfolio.
• Work⠀with⠀senior⠀leadership⠀to⠀evaluate⠀clinical⠀candidates⠀and design⠀and⠀execute⠀relevant⠀additional⠀research⠀regarding⠀the⠀mechanism⠀of action,⠀combination⠀strategies,⠀and new⠀indications.
• Serve⠀as the⠀scientific⠀lead for⠀drug⠀discovery⠀collaboration⠀and seek⠀alliances⠀with other⠀science-based⠀organizations⠀to create⠀and manage⠀effective⠀partnerships⠀that drive⠀cutting-edge⠀cancer⠀treatments⠀for⠀patients.
• Serve⠀as the⠀scientific⠀due⠀diligence⠀lead for⠀business⠀development⠀activities,⠀including⠀search and⠀evaluation,⠀licensing,⠀mergers,⠀and⠀acquisitions.
• Provide⠀guidance⠀on⠀scientific⠀matters to⠀regulatory⠀agencies,⠀scientific⠀and⠀medical⠀personnel,⠀and⠀participate⠀in the⠀preparation⠀of⠀regulatory⠀submissions⠀providing⠀science-based⠀rationale⠀for⠀actions.
• Represent⠀the⠀company⠀with⠀scientific⠀agencies⠀globally,⠀addressing⠀aspects of⠀the⠀company's⠀research⠀and⠀product⠀development.
• Perform⠀additional⠀responsibilities⠀as⠀assigned.

Required Skills & Qualifications:

• Ph.D.,⠀M.D./Ph.D.⠀in Cancer⠀Biology or⠀related⠀field from⠀an⠀accredited⠀institution⠀is⠀required.
• 20-30⠀years of⠀relevant⠀experience⠀in the⠀biopharmaceutical⠀industry,⠀15 years⠀in⠀immune-oncology⠀full-cycle⠀drug⠀development⠀(early⠀discovery⠀through⠀first-in-human⠀clinical⠀trials),⠀including⠀senior-level⠀leadership⠀experience.⠀Prior⠀experience⠀in⠀oncology⠀is⠀required.⠀Ideal if⠀the⠀candidate⠀has⠀experience⠀working⠀with⠀biologics⠀such as⠀monoclonal⠀antibodies,⠀bispecific⠀antibodies,⠀and⠀antibody-drug⠀conjugates.
• Scientific⠀broad⠀technical⠀expertise⠀in⠀oncology,⠀immunology⠀and tumor⠀biology,⠀biochemistry,⠀molecular⠀biology,⠀and⠀related⠀scientific⠀disciplines.
• Experience⠀with⠀writing⠀regulatory⠀documents⠀to support⠀IND⠀filings.
• Strong⠀written⠀and verbal⠀communication⠀skills,⠀with the⠀ability to⠀effectively⠀communicate⠀concepts⠀and ideas⠀to⠀technical⠀and⠀non-technical⠀audiences.
• Effective⠀interpersonal⠀skills,⠀with prior⠀experience⠀in⠀establishing⠀and⠀advancing⠀industry⠀partnerships⠀strongly⠀desired.
• Desired⠀experience⠀around due⠀diligence⠀of⠀business⠀development⠀opportunities.

The hiring pay range for this position is $350,000 - $500,000 per year based on skills, education, and experience relevant to the role.